10-Q
MEDICINES CO /DE filed this form 10-Q on 15 May 2002
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            Should the Parties not within three (3) months of the date of
            commencement of such good faith discussions mentioned above in this
            Article 14.2 have managed to reach a mutually acceptable solution to
            TMC's concerns, then TMC may terminate this Agreement by giving
            ninety (90) days written notice.

14.3.       Termination for Breach. In the event that either Party (the
            "Breaching Party") shall be in significant default in the
            performance of any of its material obligations under this Agreement,
            in addition to any other right and remedy the other Party (the
            "Complaining Party") may have, the Complaining Party may terminate
            this Agreement by sixty (60) days prior written notice (the "Notice
            Period") to the Breaching Party, specifying the breach and its claim
            of right to terminate, provided always that the termination shall
            not become effective at the end of the Notice Period if the
            Breaching Party cures the breach complained about during the Notice
            Period.

14.4.       Survival of Obligations. Termination or expiration of this Agreement
            shall not relieve either Party from any obligation incurred
            hereunder prior thereto.

14.5.       Survival of Provisions upon Termination and/or Expiration. Subject
            to what is stated in Article 15, the provisions of Articles 1, 7.1,
            7.2, 10, 11, 12, 13, 14.5, 15, 17 and 18 shall survive termination
            or expiration of this Agreement. The provisions of Article 2.5 shall
            survive only upon expiration of this Agreement. The provisions of
            Article 11 shall survive termination or expiration of this Agreement
            and shall continue to be in force for a period of five (5) years
            after termination or expiration of this Agreement.