MEDICINES CO /DE filed this form 10-Q on 15 May 2002
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17.5.       Agency, Partnership or Joint Venture Excluded.

17.5.1.     Nothing in this Agreement shall be construed so as to constitute
            either Party to be the agent of the other.

17.5.2.     Nothing in this Agreement and no action taken by the Parties
            pursuant to this Agreement shall constitute a partnership or joint
            venture of any kind between the Parties.

17.6.       Entire Agreement. Each of the Parties acknowledges and agrees that
            in entering into this Agreement, and the documents referred to in
            it, it does not rely on, and shall have no remedy in respect of, any
            statement, representation, warranty or understanding (whether
            negligently or innocently made) of any Person (whether party to this
            Agreement or not) other than as expressly set out in this Agreement
            as a warranty. Nothing in this Article shall either operate to limit
            or exclude any liability for fraud.

17.7.       Agreement to Supersede earlier Agreements. The Confidential
            Disclosure Agreement entered into by and between the Parties on 9
            April 2001 ceases to have effect from the date of this Agreement,
            except such termination does not affect a Party's accrued rights and
            obligations at the date of termination.

17.8.       Amendments. No amendment to or variation of this Agreement shall be
            valid unless it is in writing and signed by or on behalf of each of
            the Parties.

17.9.       Publicity and Announcements.

17.9.1.     Subject to Article 17.9.2 no press release, announcement or any
            other communication to any Third Party concerning the transaction
            contemplated by this Agreement, the financial terms of this
            Agreement, the subject matter of this Agreement or any ancillary
            matters shall be made or permitted or authorized to be made by
            either Party without the prior written approval of the other, such
            approval not to be unreasonably withheld or delayed and