10-Q
MEDICINES CO /DE filed this form 10-Q on 15 May 2002
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PATENT FAMILY LIST

Family         :   A2004
Appl./Propr    :   AstraZeneca AB
Title          :   NEW MANUFACTURING PROCESS



<TABLE>
<CAPTION>
Country             SN     F   App No            App Date        Pat No.           Grant Dt.       Exp. Dt        Status
-------             --     -   ------            --------        -------           ---------       -------        ------
<S>                 <C>    <C> <C>   <C>         <C>             <C>               <C>             <C>            <C>  
Australia           1      P   20105/00          22.11.1999                                                       Filed
Canada              1      P   2349195           22.11.1999                                                       Filed
European Pat        1      X   99963732.5        22.11.1999                                                       Filed
Hong Kong           1          [**]              [**]                                                             Filed
New Zealand         1      P   511503            22.11.1999                                                       Filed
United States       1      P   09/508260         22.11.1999                                                       Filed
South Africa        1      P   2001/3434         22.11.1999                                                       Filed
</TABLE>